4 months ago ------------- ORDER LINK FOR TRAMADOL -------------- A centrally acting analgesic (pain reliever) called tramadol is used to treat moderate to severe pain. Although it is categorized as an opioid analgesic, it differs from conventional opioids in a few ways. In situations where other painkillers might not work as well, tramadol is utilized. Tramadol's analgesic effects are partly attributed to its inhibition of serotonin and norepinephrine reuptake, which occurs in conjunction with its binding to mu-opioid receptors in the brain and spinal cord.