creativebiomart
3 years ago

The product is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII) products such as Moroctocog alfa. Factor VIII is a blood coagulant factor involved in the intrinsic pathway to form fibrin, or a blood clot. The product is a first commercially available rFVIII-Fc fusion protein (rFVIIIFc) where the conjugated molecule of rFVIII to polyethylene glycol is covalently fused to the dimeric Fc domain of human immunoglobulin G1, a long-lived plasma protein. The B domain of factor VIII is deleted. Efmoroctocog alfa https://www.creativebiomart.net/therapeutic-proteins/p/65/recombinant-factor-viii-fc-fusion-protein-rfviiifc/